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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
17.88
Human Site:
T457
Identified Species:
30.26
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
T457
V
Q
P
Y
Q
D
Q
T
Y
Q
S
V
Y
F
V
Chimpanzee
Pan troglodytes
XP_508221
618
67613
T547
V
Q
P
Y
Q
D
Q
T
Y
Q
S
V
Y
F
V
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
F420
T
T
F
Q
E
A
Y
F
V
S
E
S
F
E
E
Dog
Lupus familis
XP_855547
495
55650
T424
V
Q
P
Y
Q
D
Q
T
Y
Q
S
V
Y
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
T427
V
Q
P
Y
Q
D
Q
T
Y
Q
P
V
Y
F
V
Rat
Rattus norvegicus
P04177
498
55948
T427
V
Q
P
Y
Q
D
Q
T
Y
Q
P
V
Y
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
E497
V
Q
K
Y
G
I
T
E
F
Q
P
I
Y
F
V
Chicken
Gallus gallus
P70080
445
51121
F375
T
T
F
Q
E
V
Y
F
V
S
E
S
F
E
E
Frog
Xenopus laevis
Q92142
481
55388
F411
T
S
F
Q
E
L
Y
F
V
S
E
S
F
E
E
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
Y419
Q
P
Y
Q
D
Q
T
Y
Q
P
V
Y
F
V
S
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
P406
Y
Q
D
Q
T
Y
Q
P
V
Y
F
V
S
E
S
Fruit Fly
Dros. melanogaster
P18459
579
65977
E505
V
Q
P
Y
Q
D
Q
E
Y
Q
P
I
Y
Y
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
F387
T
E
Y
Q
P
K
Y
F
L
A
E
S
F
A
S
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
N451
I
Q
E
Y
Q
D
K
N
Y
Q
P
I
Y
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
46.6
0
0
0
20
73.3
N.A.
0
60
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
60
13.3
13.3
6.6
20
86.6
N.A.
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
22
0
0
15
0
0
29
0
0
29
22
% E
% Phe:
0
0
22
0
0
0
0
29
8
0
8
0
36
50
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
22
0
0
0
% I
% Lys:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
43
0
8
0
0
8
0
8
36
0
0
0
0
% P
% Gln:
8
65
0
43
50
8
50
0
8
58
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
22
22
29
8
0
22
% S
% Thr:
29
15
0
0
8
0
15
36
0
0
0
0
0
0
0
% T
% Val:
50
0
0
0
0
8
0
0
29
0
8
43
0
8
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
15
58
0
8
29
8
50
8
0
8
58
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _